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J Infect Dis ; 218(10): 1622-1630, 2018 10 05.
Artículo en Inglés | MEDLINE | ID: mdl-29917112

RESUMEN

Background: A mobile laboratory transportable on commercial flights was developed to enable local response to viral hemorrhagic fever outbreaks. Methods: The development progressed from use of mobile real-time reverse-transcription polymerase chain reaction to mobile real-time recombinase polymerase amplification. In this study, we describe various stages of the mobile laboratory development. Results: A brief overview of mobile laboratory deployments, which culminated in the first on-site detection of Ebola virus disease (EVD) in March 2014, and their successful use in a campaign to roll back EVD cases in Conakry in the West Africa Ebola virus outbreak are described. Conclusions: The developed mobile laboratory successfully enabled local teams to perform rapid disgnostic testing for viral hemorrhagic fever.


Asunto(s)
Fiebre Hemorrágica Ebola/diagnóstico , Laboratorios , Unidades Móviles de Salud , Sistemas de Atención de Punto , África Occidental , Ebolavirus/genética , Fiebre Hemorrágica Ebola/virología , Humanos , Tipificación Molecular/instrumentación , ARN Viral/sangre , Reacción en Cadena en Tiempo Real de la Polimerasa/instrumentación
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